Warfarin (Coumadin) Questions With Answers NCLEX Exam 2026

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Warfarin (Coumadin) Questions With Answers NCLEX Exam 2025

1. Warfarin (Coumadin) is an anticoagulant. What family of anticoagulant medications does this drug belong to?

A. Direct thrombin inhibitors

B. Indirect thrombin inhibitors

C. Vitamin K antagonists

D. Factor Xa inhibitors

The answer is C. Warfarin (Coumadin) is an anticoagulant that belongs to the Vitamin K antagonists.

2. Which statement below BEST describes how Warfarin (Coumadin) works as an anticoagulant?

A. “It inhibits the formation of thrombin and fibrin in the clotting process.”

B. “It increases the production of Factor Xa, which blocks thrombin and decreases the clotting process.”

C. “It binds to antithrombin and reverses the clotting process.”

D. “It stops the coagulation process by blocking the formation of clotting factors in the liver that require Vitamin K to form.”

The answer is D. Warfarin (Coumadin) stops the coagulation process by blocking the formation of clotting factors in the liver that require Vitamin K to form. This is why this drug is part of the Vitamin K antagonist family.

3. You’re educating a patient’s family member about Warfarin (Coumadin) and how it is used to treat blood clots. Which statements by the family member require you to re-educate them about how this medication works? Select all that apply:

A. “This medication will help dissolve the blood clot.”

B. “This medication will prevent another blood clot from forming.”

C. “This medication will help prevent the blood clot from becoming bigger in size.”

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