Barbiturates (Anxiolytic and Sedative-Hypnotic) NCLEX Nursing Questions (NCLEX EXAM 2026)

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Barbiturates (Anxiolytic and Sedative-Hypnotic) NCLEX Nursing Questions

1. Which statement below is INCORRECT about Barbiturates?

A. “Barbiturates are not as commonly prescribed today for conditions like anxiety or insomnia. Instead they’ve been replaced by the Benzodiazepines which have a lower risk of toxicity.”

B. “Barbiturates have a low therapeutic index.”

C. “Barbiturates decrease the effects of GABA.”

D. “Barbiturates are a central nervous system depressant.”

The answer is C. This is a false statement. It should say, “Barbiturates INCREASE the effects of GABA.”

2. Select all the medications below that are classified as a Barbiturate:

A. Midazolam

B. Phenobarbital

C. Primidone

D. Lorazepam

The answers are B and C. Phenobarbital and Primidone are both Barbiturates. Midazolam and Lorazepam are Benzodiazepines.

3. Which Barbiturate below can be prescribed for migraines and is used in combination with Acetaminophen and/or Caffeine?

A. Secobarbital

B. Diazepam

C. Butalbital

D. Temazepam

The answer is C: Butalbital

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