MN552 Midterm VERIFIED QUIZ ANSWERS 2024,2026

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What is Modified Release? The term modified-release is used to describe dosage forms that alter the timing and/or the rate of release of a conventional drug product/dosage form - FDA does define this Some Modified Release Systems - some of these have overlap 1. Delayed release 2. Repeated Release or Repeat Action 4. Extended, Sustained, Long-Acting, Prolonged, Controlled Release 5. Targeted Release Delayed-release - dosage forms release the drug at a later time than an immediate dose system - Delayed-release can include enteric-coated tablets, where timed release is achieved by a barrier coating - takes more time to release drug; doesn't start dissolving until a certain point of time Repeat-release - multiple doses of immediate release drug units with intermittent dosing - Such as repeat-action tablets and capsules Extended, Sustained, Long-Acting, Prolonged, Controlled Release - Extended, Sustained-release systems slowly release the drug over an extended period of time - Rate and duration are not always designed to a particular profile - If the system can maintain predictable levels of drug in the target tissue or cells, it is considered controlled- release. (Examples: XL,SR,CR) - Controlled release systems are also called extended or sustained (prolonged) release - dissolves and continues dissolving for a longer time

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