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  • Intrinsic and Extrinsic Coagulation Pathways Verified Answers 2025/2026

Intrinsic and Extrinsic Coagulation Pathways Verified Answers 2025/2026

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Describe the release of Tissue Factor Triggers coagulation (thromboplastin) released or exposed when endothelial cells are damaged at the site of injury Is a membrane bound glycoprotein produced by endothelial cells interacts with factor VII to produce VIIa (extrinsic pathway) that in turn triggers activation of the coagulation cascade Describe clot formation and stabilization (secondary hemostasis) activation of the coagulation cascade (involving tissue factor) results in fibrin formation, cementing the platelets into a stable larger hemostatic plug Describe procoagulant factors and their function inactive proteins made by the liver Cleaved in a series of proteolytic steps to active enzymes Activated factors have an "a" following their names

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Item Information

  • Uploaded

    19 January 2024

  • Updated

    05 January 2026

  • Category

    Accounting

  • Item Type

    exam

  • Tags

    Intrinsic and Extrinsic Coagulation Pathways coagulation thromboplastin secondary hemostasis clot formation procoagulant factors

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