
Passing Grades Flashcards
1. amino acid tryptophan is transported into the brain from the plasma as 5HT precursor
2. tryptophan hydroxylase (TRY-OH) converts tryptophan into 5-hydroxytryptophan (5HTP),
3. then aromatic amino acid decarboxylase (AAADC) converts 5HTP into 5HT
4. 5HTis then taken up in the synaptic vesicle via VMAT2, until release p. 142
2. tryptophan hydroxylase (TRY-OH) converts tryptophan into 5-hydroxytryptophan (5HTP),
3. then aromatic amino acid decarboxylase (AAADC) converts 5HTP into 5HT
4. 5HTis then taken up in the synaptic vesicle via VMAT2, until release p. 142
1. serotonin neurons whose cell bodies are in the midbrain raphe that innervate nigrostriatal dopamine neuros both at the level of the dopamine neuronal cell bodies in the substantia nigra
2. at the dopamine neuronal axon terminals in the striatum
3. This innervation may be either direct connection between the serotonin neuron and the dopamine dopamine neuron or
via an indirect connection with a GABA interneuronp. 143
2. at the dopamine neuronal axon terminals in the striatum
3. This innervation may be either direct connection between the serotonin neuron and the dopamine dopamine neuron or
via an indirect connection with a GABA interneuronp. 143
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