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Test Bank for Pharmacology 7th Edition by Hitner
Chapter 01
Introduction to Pharmacology
Multiple Choice Questions
1. Pharmacokinetics is the area of pharmacology that deals with the study of: A. the processes of drug absorption, distribution, metabolism, and excretion.
B. the action of drugs on living tissue.
C. the use of drugs in treating disease.
D. the harmful effects of drugs on living tissue.
Pharmacokinetics is the area of pharmacology that deals with the study of the processes of drug absorption, distribution, metabolism, and excretion.
ABHES: 6.a. Identify drug classification, usual dose, side effects, and contraindications of the top most commonly used medications Blooms: Remember
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 1 Easy Learning Outcome: 01.01
2. Which of the following is an example of a drug derived from a plant?
A. Insulin
B. Digitalis
C. Cephalosporin D. Estradiol
Examples of drugs derived from plants that are still widely used today include the analgesics morphine and codeine, which were obtained from the poppy plant (Papver somniferum); the heart drug digitalis, which was obtained from the purple foxglove (Digitalis purpurea); and the antimalarial drug quinine, which was obtained from the bark of the cinchona tree.
ABHES: 6.a. Identify drug classification, usual dose, side effects, and contraindications of the top most commonly used medications Blooms: Remember
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 1 Easy
Learning Outcome: 01.01
3. Today, new drugs are mainly derived from: A. chemical synthesis.
B. animals.
C. plants.
D. enzymatic synthesis.
Despite the many examples of drugs obtained from plants and living organisms, the main source of new drugs today is from chemical synthesis.
ABHES: 6.a. Identify drug classification, usual dose, side effects, and contraindications of the top most commonly used medications Blooms: Remember
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 1 Easy
Learning Outcome: 01.01
4. Which of the following statements is true of toxicity?
A. Toxic effects refer to those effects triggered by drugs that are undesirable but not harmful.
B. The toxic effects of a drug can be life-threatening.
C. The toxic effects of a drug can be controlled by increasing the dosage of the drug.
D. Patients are often advised to tolerate the toxicity of a drug in order to benefit from the drug's therapeutic actions.
Toxic effects, or toxicity, implies drug poisoning, the consequences of which can be extremely harmful and may be life-threatening.
ABHES: 6.d. Properly utilize Physician’s Desk Reference (PDR), drug handbook and other drug references to identify a drug’s classification, usual dosage, usual side effects, and contraindications.
Blooms: Understand
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 2 Medium
Learning Outcome: 01.02
5. Which of the following statements is true of a drug?
A. The effects produced by a drug are always desirable.
B. The properties of a drug do not influence the effects it produces.
C. A drug does not produce more than one effect.
D. A pure drug is a chemical compound with a specific chemical structure.
Every pure drug is a chemical compound with a specific chemical structure.
ABHES: 6.a. Identify drug classification, usual dose, side effects, and contraindications of the top most commonly used medications Blooms: Understand
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 2 Medium
Learning Outcome: 01.02
6. Maria visits Dr. John's clinic for a medical consultation. After learning that Maria has been experiencing a severe case of cold and cough, Dr. John conducts a thorough physical examination and prescribes a cough syrup and cetirizine tablets for her symptoms. A few days later, Maria calls Dr. John and informs him that the medication has been making her feel drowsy. How is Dr. John most likely to respond?
A. He will ask Maria to start taking a different dosage of cetirizine.
B. He will advise Maria to bear with the effects of the medication in order to benefit from its therapeutic actions.
C. He will advise Maria to stop taking the tablets immediately and to visit his clinic for another examination.
D. He will ask Maria to stop taking the drug and immediately rush to her house to administer an antidote.
In this case, Maria is most likely experiencing the side effects of the drug. Many side effects are more of a nuisance than they are harmful. Dr. John will advise Maria to bear with the side effects of the medication in order to benefit from its therapeutic actions.
ABHES: 6.a. Identify drug classification, usual dose, side effects, and contraindications of the top most commonly used medications Blooms: Analyze
CAAHEP: I.C.11.c. Identify the classifications of medications including side effects Difficulty: 3 Hard
Learning Outcome: 01.02
7. Examples of common adverse effects include all of the following except: A. persistent diarrhea.
B. vomiting.
C. confusion.
D. anaphylaxis.
Adverse effects are also undesired effects, but these are effects that may be harmful (persistent diarrhea, vomiting, or central nervous system disturbances such as confusion) or that with prolonged treatment may cause conditions that affect the function of vital organs such as the liver or kidney.
ABHES: 6.d. Properly utilize Physician’s Desk Reference (PDR), drug handbook and other drug references to identify a drug’s classification, usual dosage, usual side effects, and contraindications.
Blooms: Understand
CAAHEP: I.C.11.d. Identify the classifications of medications including adverse reactions Difficulty: 1 Easy
Learning Outcome: 01.02
8. Drugs that bind to specific receptors and produce a drug action are called _____. A. repressors
B. antagonists
C. agonists
D. modulators
Drugs that bind to specific receptors and produce a drug action are called agonists.
ABHES: 6.d. Properly utilize Physician’s Desk Reference (PDR), drug handbook and other drug references to identify a drug’s classification, usual dosage, usual side effects, and contraindications.
Blooms: Remember
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 1 Easy
Learning Outcome: 01.03
9. A group of interns at Wingsdale Hospital are watching Dr. Gerald and his team perform a surgery. During the surgery, Dr. Gerald resuscitates his patient from cardiac arrest by giving her an intravenous injection of epinephrine. As soon as the patient's condition improves, Dr. Gerald explains to his interns that when epinephrine binds to the beta receptors of the heart, it triggers an increase in heart rate and blood pressure. Based on the information provided in this scenario, we can conclude that epinephrine is acting as a(n): A. antagonist.
B. modulator.
C. agonist.
D. partial antagonist.
Based on the information provided in this scenario, we can conclude that epinephrine is acting as an agonist. Drugs that bind to specific receptors and produce a drug action are called agonists.
ABHES: 6.d. Properly utilize Physician’s Desk Reference (PDR), drug handbook and other drug references to identify a drug’s classification, usual dosage, usual side effects, and contraindications.
Blooms: Apply
CAAHEP: I.C.11.b. Identify the classifications of medications including desired effects Difficulty: 3 Hard
Learning Outcome: 01.03
CAAHEP: I.P.4.c. Verify the rules of medication administration right dose CAAHEP: II.C.2. Apply mathematical computations to solve equations
Difficulty: 3 Hard
Learning Outcome: 01.05
26. Three medications have the following therapeutic index values: 2, 4, and 0.5. Which medication is the safest?
A. The medication with the therapeutic index value of 0.5
B. The medication with the therapeutic index value of 2
C. The medication with the therapeutic index value of 4
D. None of these medications
The therapeutic index (TI) is a ratio of the lethal dose 50 (LD50) to the effective dose 50 (ED50) of a drug. A therapeutic index value of four indicates that four times as much drug is needed to produce a lethal effect in 50 percent of the animals as is needed to produce the therapeutic effect in 50 percent of the animals.
ABHES: 6.d. Properly utilize Physician’s Desk Reference (PDR), drug handbook and other drug references to identify a drug’s classification, usual dosage, usual side effects, and contraindications.
Blooms: Analyze
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use
CAAHEP: I.P.4.b. Verify the rules of medication administration right medication CAAHEP: I.P.4.c. Verify the rules of medication administration right dose
Difficulty: 3 Hard
Learning Outcome: 01.05
27. Which of the following would not be considered a dose-dependent adverse effect of a drug? A. Nausea
B. Liver damage
C. Kidney damage D. Idiosyncrasy
A few adverse drug effects are not dose-dependent. These effects, such as drug idiosyncrasy and drug allergy, are determined by individual variation.
ABHES: 6.d. Properly utilize Physician’s Desk Reference (PDR), drug handbook and other drug references to identify a drug’s classification, usual dosage, usual side effects, and contraindications.
Blooms: Analyze
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 3 Hard Learning Outcome: 01.05
28. Drugs, such as thalidomide, that produce birth defects are known as _____.
A. mutagens
B. carcinogens
C. teratogens
D. allergens
Drugs, such as thalidomide, that produce birth defects are known as teratogens.
ABHES: 6.d. Properly utilize Physician’s Desk Reference (PDR), drug handbook and other drug references to identify a drug’s classification, usual dosage, usual side effects, and contraindications.
Blooms: Remember
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use
CAAHEP: I.C.11.d. Identify the classifications of medications including adverse reactions Difficulty: 1 Easy
Learning Outcome: 01.05
29. Which of the following statements is true of drug nomenclature?
A. The nonproprietary name of a drug is usually a contraction of its chemical name.
B. The proprietary name of a drug is more commonly referred to as the generic name.
C. A drug can have several different generic names.
D. The name under which a drug is marketed is known as its nonproprietary name.
All drugs are chemicals, and many have long chemical-names. As a result, all drugs are given a shorter name, known as the nonproprietary name, which is usually a contraction of the chemical name.
ABHES: 6.d. Properly utilize Physician’s Desk Reference (PDR), drug handbook and other drug references to identify a drug’s classification, usual dosage, usual side effects, and contraindications.
Blooms: Understand
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 2 Medium Learning Outcome: 01.06
30. The nonproprietary name of a medication is more commonly known as its _____.
A. trade name
B. generic name C. chemical name
D. brand name
The nonproprietary name is more commonly referred to as the generic name.
ABHES: 6.a. Identify drug classification, usual dose, side effects, and contraindications of the top most commonly used medications Blooms: Remember
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 1 Easy
Learning Outcome: 01.06
31. Orion laboratories, a pharmaceutical manufacturing company, manufactures the drug cetirizine and markets the tablets under the name "Alzer." In this case, cetirizine is the _____ name of the drug.
A. proprietary
B. generic
C. trade
D. brand
In the case, cetirizine is the generic name of the drug. All drugs are given a shorter name, known as the nonproprietary name, which is usually a contraction of the chemical name. The nonproprietary name is more commonly referred to as the generic name.
ABHES: 6.a. Identify drug classification, usual dose, side effects, and contraindications of the top most commonly used medications Blooms: Apply
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 2 Medium
Learning Outcome: 01.06
32. Which of the following is a drug information service that is updated on a monthly basis with the most current drug information?
A. The Physicians' Desk Reference
B. Drug Facts and Comparisons
C. The United States Pharmacopeia/National Formulary
D. Drug Information—American Hospital Formulary Service
Drug Facts and Comparisons (F&C) is a loose-leaf index that provides the most current drug information on a regular basis. Drug information and new drug additions are updated monthly.
ABHES: 6.d. Properly utilize Physician’s Desk Reference (PDR), drug handbook and other drug references to identify a drug’s classification, usual dosage, usual side effects, and contraindications.
Blooms: Understand
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use Difficulty: 1 Easy
Learning Outcome: 01.07
33. Which of the following statements is true of the United States Pharmacopeia/National Formulary (USP/NF)?
A. It is updated once in every six months.
B. It is primarily used by physicians and nurses for information relating to the use of drugs in the practice of medicine.
C. It is primarily used by drug manufacturers to ensure that drug production adheres to official government standards.
D. It provides the most current drug information on a regular basis.
The United States Pharmacopeia/National Formulary (USP/NF) is primarily used by drug manufacturers to ensure that drug production adheres to official government standards.
ABHES: 6.e. Comply with federal, state, and local health laws and regulations Blooms: Understand
CAAHEP: I.C.11.a. Identify the classifications of medications including indications for use CAAHEP: I.C.12. Identify quality assurance practices in healthcare
Difficulty: 2 Medium Learning Outcome: 01.07
34. The _____ of 1970 was designed to regulate the dispensing of drugs that have the potential to be misused.
A. Federal Food Drug and Cosmetic Act
B. Federal Pure Food and Drug Act
C. Federal Comprehensive Drug Abuse Prevention and Control Act
D. Regulated Health Professions Act
The Federal Comprehensive Drug Abuse Prevention and Control Act of 1970 was designed to regulate the dispensing of drugs, called controlled substances, that have the potential for abuse.
ABHES: 6.c.3 Comply with legal aspects of creating prescriptions, including federal and state laws
ABHES: 6.e. Comply with federal, state, and local health laws and regulations
Blooms: Remember
CAAHEP: I.C.12. Identify quality assurance practices in healthcare
Difficulty: 1 Easy
Learning Outcome: 01.07
35. In the context of the drug schedules defined in the Federal Comprehensive Drug Abuse Prevention and Control Act, identify an accurate statement about schedule I drugs.
A. These drugs are prescribed by physicians for a narrow range of medical conditions.
B. These drugs have a high potential for abuse and no accepted medical use.
C. This category of drugs includes narcotics such as morphine and pure codeine.
D. These drugs have a very low potential for abuse and are widely used in medical treatment.
Schedule I drugs have a high potential for abuse and no accepted medical use.
ABHES: 6.c.3 Comply with legal aspects of creating prescriptions, including federal and state laws
ABHES: 6.d. Properly utilize Physician’s Desk Reference (PDR), drug handbook and other drug references to identify a drug’s classification, usual dosage, usual side effects, and contraindications.
Blooms: Understand
CAAHEP: I.C.12. Identify quality assurance practices in healthcare
Difficulty: 2 Medium
Learning Outcome: 01.07
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